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🚨 HIGH-LEVEL RESISTANCE (HLR) ALERT: EUCAST Updates Gentamicin Thresholds for Enterococci! 🚨

FRCPath Prep Medical Microbiology Consultants
Aug 31
2 min read

Big changes are here, and they directly impact how you interpret enterococcal synergy testing. If you’re preparing for FRCPath Part 2, this is essential knowledge.

🔥 What’s Changed?

OLD (up to EUCAST v14.0, 2024):

High-Level Gentamicin Resistance (HLGR) was defined as MIC >128 mg/L.

NEW (EUCAST v15.0, 2025):

HLGR is now defined as MIC >512 mg/L.

Yes, you read that right—the cut-off just quadrupled! — 🚨 HIGH-LEVEL RESISTANCE (HLR) ALERT: EUCAST Updates Gentamicin Thresholds for Enterococci! 🚨

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